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DNA Amplification for Forensic Analysts


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In the United States, the development of Y-STR core loci has followed a pattern similar to the development of the CODIS core STR loci. The Scientific Working Group for DNA Analysis Methods (SWGDAM) created a subcommittee to investigate Y-STRs. The subcommittee reviewed published data and ran several hundred population database samples to evaluate various loci.

National Institute of Justice (see reuse policy).

The subcommittee established the following 11 loci as the core Y-STR loci: 

  • DYS19
  • DYS385 A/B
  • DYS389I
  • DYS389II
  • DYS390
  • DYS391
  • DYS392
  • DYS393
  • DYS438
  • DYS439
  • DYS1908

With the establishment of the core loci, manufacturers have the specifications needed for the development of Y-STR kits

European laboratories have also established core Y-STR loci for forensic testing. ENFSI decided to use the same loci as the United States, minus DYS438 and DYS439.09

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