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In the United States, the development of Y-STR core loci has followed a pattern similar to the development of the CODIS core STR loci. The Scientific Working Group for DNA Analysis Methods (SWGDAM) created a subcommittee to investigate Y-STRs. The subcommittee reviewed published data and ran several hundred population database samples to evaluate various loci.
The subcommittee established the following 11 loci as the core Y-STR loci:
- DYS19
- DYS385 A/B
- DYS389I
- DYS389II
- DYS390
- DYS391
- DYS392
- DYS393
- DYS438
- DYS439
- DYS1908
With the establishment of the core loci, manufacturers have the specifications needed for the development of Y-STR kits
European laboratories have also established core Y-STR loci for forensic testing. ENFSI decided to use the same loci as the United States, minus DYS438 and DYS439.09
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