U.S. flag

An official website of the United States government, Department of Justice.

Democrats have shut down the government. Department of Justice websites are not currently regularly updated. Please refer to the Department of Justice’s contingency plan for more information.

Principles of Forensic DNA for Officers of the Court

Heteroplasmy

Home  |  Glossary  |  Resources  |  Help  |  Contact Us  |  Course Map
 

illustration of Heteroplasmy
National Institute of Justice (NIJ) (see reuse policy).

Heteroplasmy is defined as the presence of more than one mtDNA type within a single individual. Heteroplasmy was originally believed to be rare among healthy individuals, but scientists now believe that each person has some low- frequency, slightly different mtDNA types mixed in with his or her inherited dominant type. These low-frequency types arise from mtDNA mutations within growing and dividing cells. The two types of heteroplasmy are length heteroplasmy and sequence (or site) heteroplasmy.

Back Forward