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A mutation occurs when DNA is damaged or changed anywhere along the DNA strand. Mutations that occur in primer-binding site regions or along the STR region can complicate interpretation.
The following are types of mutations that can occur:
Types of Mutations | |
|---|---|
| Mutation | Description |
| Insertion | A base is inserted or added to the original DNA strand |
| Deletion | A base is deleted or removed from the original DNA strand |
| Transition | A transition between purine or pyrimidine bases occur in the original DNA strand
Transitions are more common than transversions |
| Transversion | A transversion between purine and pyrimidine bases occur in the original DNA strand
|
Additional Online Courses
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- Non-STR DNA Markers: SNPs, Y-STRs, LCN and mtDNA
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- Laboratory Orientation and Testing of Body Fluids and Tissues
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Date Created: July 11, 2023