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AmpFLP (D1S80) visualized using silver staining
The next phase in the development of DNA for use in forensic science returned to the concept of VNTRs. Some VNTR regions are relatively short and can be amplified by PCR.
Sometimes called AmpFLPs (amplified fragment poymorphisms), examples that were evaluated for use in crime laboratories included:
- D1S80
- YNZ 22 (D17S5)
- 3'ApoB
AmpFLPs did not have the discrimination power of RFLP or the simplicity of DQ-Alpha/Polymarker and were not widely used.
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Date Created: June 16, 2023