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Forensic biology

Genes of a Feather Stick Together: Evaluating Linked Markers

March 2018

New DNA analysis kits used in kinship testing may contain loci that are potentially linked. This project will examine if three pairs of exhibit linkage and explore possible solutions for using these loci more appropriately in kinship testing.

This webinar was presented by the NIJ Forensic Technology Center of Excellence on March 28, 2018.

Rapid DNA’s Role in Disaster Victim Identification

May 2019

The Department of Homeland Security Science and Technology Directorate has tested Rapid DNA at mass fatality incident response exercises since 2015. This was done to determine the technology’s ability and usefulness in identifying victims of mass disasters. This webinar will review the successes and challenges from those exercises as well as discuss Rapid DNA’s most recent role in identifying victims of the 2018 Camp Fire in Butte County, CA.

This webinar was presented by the NIJ Forensic Technology Center of Excellence on May 2, 2019.

Emerging Forensic Research Series: Forensic Biology

April 2019

Forensic science research and development plays a key role in the advancement of the practice of forensic science, as noted by the 2009 National Academies of Science report “Strengthening Forensic Sciences in the United States: A Path Forward.”

This webinar was presented by the NIJ Forensic Technology Center of Excellence on April 9, 2019.

New Scientific Working Group on DNA Analysis Methods (SWGDAM) Recommendations on Communicating Likelihood Ratios

October 2018

SWGDAM recently issued recommendations on genotyping results reported as likelihood ratios, designed to promote consistency among laboratories. Members of the committee will discuss the recommendations and their foundations.

This webinar was presented by the NIJ Forensic Technology Center of Excellence on October 18, 22018.

An Automated Single Cell Separation Technique to Improve Mixture Deconvolution

November 2020

This webinar will provide an evaluation of the DEPArray™, a system that enables the identification, separation, and recovery of single cells or groups of cells from heterogeneous mixtures. The workflow described in this webinar will highlight the impact this instrument, with standard forensic processes, will have on processing sexual assault evidence and improving the success of single cell analyses.

Effects of DNA Extraction Methods on Recovery, Degradation, and Loss

August 2020

Many working with genomic DNA can afford to lose large portions of it during its extraction without negatively impacting downstream analysis.  However, with work targeting highly degraded DNA sources, retention of every molecule can be key to successful analyses.   This webinar addressed the insufficient documentation of absolute efficiencies of extraction methods and the nature of DNA loss associated with the study of low copy number and degraded DNA samples.

Validation and Tutorial of NOCIt for Determining the Number of Contributors

July 2020

This webinar highlighted the results of a full developmental validation of a method that estimates the A Posteriori Probability (APP) of the number of contributors in a DNA sample(NOC), and demonstrated that estimating the APP based on peak heights outperforms methods that rely on binary determinations alone. This presentation focused on including the true NOC in Likelihood Ratio interpretations and on repeatability.

This webinar was presented by the NIJ Forensic Technology Center of Excellence on July 14, 2020.

The Time to Collect is Now: DNA Evidence in Groping Sexual Assault Cases

February 2019

Improving the overall response to sexual assault includes understanding how touch DNA evidence impacts groping sexual assault cases. This webinar will illustrate the importance of these cases and highlight proposed guidelines for evidence collection.

This webinar was presented by the NIJ Forensic Technology Center of Excellence on February 27, 2019.

Investigative Genetic Genealogy: Background and Crime Lab Strategy

January 2020

In this webinar we discussed the theory and development of Investigative Genetic Genealogy, including some ethical and legal considerations raised by this technique.  Additionally, we explored the current status of case investigations, the impact on crime laboratories, implementation strategies, and recommendations for jurisdictions considering applying Investigative Genetic Genealogy to their unsolved cases.

This webinar was presented by the NIJ Forensic Technology Center of Excellence on January 23, 2020. 

Molecular Identification of Insects Relevant to Medicolegal Casework

December 2021

Molecular identification is advantageous for medicolegal death investigations involving entomological activity. This enables species-level identification of immature specimens necessary for estimating post-mortem interval and may be performed without specialized training or resources. The presenter describes a strategy effective for relevant species and demonstrates analysis of casework-type samples.

This webinar was presented by the NIJ Forensic Technology Center of Excellence on December 2, 2021.

Microhaplotypes: A Comprehensive Forensic DNA Marker

June 2021

Microhaplotypes (microhaps) are biomarkers fewer than 300 nucleotides long that display multiple allelic combinations. The main advantages of microhaps over conventional short tandem repeats (STRs) include the 1) absence of stutter, 2) same-size alleles within each locus, 3) lower mutation rate, and 4) ancestry informative alleles. These forensically relevant loci can yield a power of discrimination similar to STRs while enhancing human identification (HID), mixture deconvolution, and biogeographic ancestry prediction.

Stability and Persistence of Touch DNA for Forensic Analysis

March 2021

Touch DNA is a potentially powerful sample type for forensic casework, but is challenging to work with due to low quantity, variable deposition amounts, and fundamental questions regarding stability over time. In this webinar we describe best-practices and initial results related to comprehensive studies of the stability of touch DNA after exposure to different environmental conditions.

This webinar was presented by the NIJ Forensic Technology Center of Excellence on March 11, 2021.