U.S. flag

An official website of the United States government, Department of Justice.

Current State of Knowledge on Implications of Gut Microbiome for Surgical Conditions

NCJ Number
253160
Date Published
2018
Length
12 pages
Author(s)
Edmund B. Chen; Cori Cason; Jack A. Gilbert; Karen J. Ho
Agencies
NIJ-Sponsored
Publication Type
Research (Applied/Empirical), Report (Study/Research), Report (Grant Sponsored), Program/Project Description
Grant Number(s)
2017-MU-MU-0042
Annotation
This article provides a broad overview of the current state of knowledge on the implications of gut microbiome for surgical conditions, and the technology that helped in their formation is reviewed.
Abstract
The role of the microbiome in human health has become a central tenant of current medical research, infiltrating a diverse disciplinary base whereby microbiology, computer science, ecology, gastroenterology, immunology, neurophysiology and psychology, metabolism, and cardiovascular medicine all intersect. Traditionally, commensal gut microbiota have been assumed to play a significant role only in the metabolic processing of dietary nutrients and host metabolites, the fortification of gut epithelial barrier function, and the development of mucosal immunity; however, over the last 20 years, new technologies and renewed interest have uncovered a considerably broader influence of the microbiota on health maintenance and disease, many of which are of particular relevance for surgeons. (publisher abstract modified)
Date Created: July 20, 2021