Real-Time Sample-Mining and Data-Mining Approaches for the Discovery of Novel Psychoactive Substances (NPS)

Award Information

Awardee

THE FREDRIC RIEDERS FAMILY RENAISSANCE FOUNDATION

Award #

2020-DQ-BX-0007

Funding Category

Competitive Discretionary

Location

HORSHAM, PA

Congressional District

Status

Past Project Period End Date

Funding First Awarded

2020

Total funding (to date)

$755,401

Original Funding Opportunity

Research and Development in Forensic Science for Criminal Justice Purposes, Fiscal Year 2020

Grant-Funded Publications

Toxicological Evaluation, Postmortem Case Descriptions, and Pharmacological Activity of N,N-dimethylpentylone and Related Analogs
Journal: Journal of Analytical Toxicology

Date Published: January 2025
Evaluating Cross-reactivity of New Psychoactive Substances (NPS) in Human Whole Blood by Enzyme-linked Immunosorbent Assay (ELISA)
Journal: Journal of Analytical Toxicology

Date Published: March 2024
Fighting the Uphill War Against Illicit Drugs and Overdose Deaths: Detecting Emerging Designer Drugs and Opioid Analogs
Date Published: September 2023
N,N-Dimethylpentylone (dipentylone)—A new synthetic cathinone identified in a postmortem forensic toxicology case series
Journal: Journal of Analytical Toxicology

Date Published: June 2023
Detection in seized samples, analytical characterization, and in vitro metabolism of the newly emerged 5-bromo-indazole-3-carboxamide synthetic cannabinoid receptor agonists
Journal: Drug Testing and Analysis

Date Published: 2023
Detection, chemical analysis, and pharmacological characterization of dipyanone and other new synthetic opioids related to prescription drugs
Journal: Analytical and Bioanalytical Chemistry

Date Published: 2023
In vitro cannabinoid receptor activity, metabolism, and detection in seized samples of CH-PIATA, a new indole-3-acetamide synthetic cannabinoid
Journal: Drug Testing and Analysis

Date Published: 2023
New Potent Synthetic Opioid—N-Desethyl Isotonitazene—Proliferating Among Recreational Drug Supply in USA
Date Published: 2023
NPS Discovery Q2 2023 Trend Reports
Date Published: 2023
Plasma pharmacokinetics and pharmacodynamic effects of the 2-benzylbenzimidazole synthetic opioid, isotonitazene, in male rats
Journal: PSYCHOPHARMACOLOGY

Date Published: 2023
Positivity of New Synthetic Cannabinoid 4F-MDMB-BICA Increasing in U.S. as Prevalence of 5F-MDMB-PICA Wanes
Date Published: 2023
Proliferation of Novel Synthetic Opioids in Postmortem Investigations After Core-Structure Scheduling for Fentanyl-Related Substances
Journal: American Journal of Forensic Medicine and Pathology

Date Published: December 2022
A Forward-Thinking Approach to Addressing the New Synthetic Opioid 2-Benzylbenzimidazole Nitazene Analogs by Liquid Chromatography-Tandem Quadrupole Mass Spectrometry (LC-QQQ-MS)
Journal: Journal of Analytical Toxicology

Date Published: April 2022
Pharmacological Evaluation and Forensic Case Series of N-pyrrolidino Etonitazene (etonitazepyne), a Newly Emerging 2-benzylbenzimidazole 'Nitazene' Synthetic Opioid
Journal: Archives of Toxicology

Date Published: April 2022
Toxicological and Pharmacological Characterization of Novel Cinnamylpiperazine Synthetic Opioids in Humans and in Vitro Including 2-methyl AP-237 and AP-238
Journal: Archives of Toxicology

Date Published: March 2022
Bromazolam Prevalence Surging Across the United States Driven In Part by Increasing Detections Alongside Fentanyl
Date Published: 2022
N,N-Dimethylpentylone (NPS Stimulant)
Date Published: 2022
N-Pyrrolidino Etonitazene (NPS Opioid)
Date Published: 2022
NPS Discovery: 2022 Year in Review
Date Published: 2022
Synthetic Stimulant Market Rapidly Changing as N,N-Dimethylpentylone Replaces Eutylone in Drug Supply Typically Sold as "Ecstasy" or "Molly"
Date Published: 2022
Etodesnitazene — New Synthetic Opioid Identified During Forensic Death Investigations in the United States and Canada
Date Published: 2021
Metonitazene (NPS Opioid)
Date Published: 2021
Metonitazene Begins Proliferation as Newest Synthetic Opioid Among Latest Cycle of Non-Fentanyl Related Drugs
Date Published: 2021
Metonitazene in the United States-Forensic toxicology assessment of a potent new synthetic opioid using liquid chromatography mass spectrometry
Journal: Drug Testing and Analysis

Date Published: 2021
New High Potency Synthetic Opioid N-Pyrrolidino Etonitazene (Etonitazepyne) Linked to Overdoses Across United States
Date Published: 2021
New Synthetic Opioid Protonitazene Increasing in Prevalence as "Nitazenes" Gain Traction Across the United States and Canada
Date Published: 2021
New Systematic Naming for Synthetic Cannabinoid “MDA-19” and Its Related Analogues: BZO-HEXOXIZID, 5F-BZO-POXIZID, and BZO-POXIZID
Date Published: 2021
NPS Discovery: 2021 Year in Review
Date Published: 2021

Date Created: October 22, 2020

Real-Time Sample-Mining and Data-Mining Approaches for the Discovery of Novel Psychoactive Substances (NPS)

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Award Information

Similar Awards

Real-Time Sample-Mining and Data-Mining Approaches for the Discovery of Novel Psychoactive Substances (NPS)

Award Information

Supplemental Award 1 (Fiscal Year 2022, $200,000)

Grant-Funded Publications

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