Articles Published by NIJ

“Wherever he steps, whatever he touches, whatever he leaves, even unconsciously, will serve as a silent witness against him.” Edmond Locard (1877-1966), forensic science pioneer

Researchers improve molecular autopsy accuracy by identifying more genetic variants that could lead to sudden unexplained deaths. These genetic clues may better inform criminal investigations and help prevent deaths in surviving family members.

Identifying individuals through next generation DNA sequencing may involve degraded or mixed samples. A researcher has developed a technique to make fragmented DNA more readable, and a method to help pull individual profiles from mixed samples.

The forensic power of DNA is clear, but biological evidence also contains RNA, another potential source of information. Because RNA decomposes quickly, its utility is considered limited. Could this decomposition provide information about a sample’s age?

The regions of the genome relied on for identification of individuals pose challenges for analysts because they often produce artifacts during processing. NIJ-funded research has led to a solution that lessens the artifact problem.

Key questions have arisen about how DNA data are to be interpreted statistically. Two NIJ grants have supported research that has far-reaching implications for testing hypotheses using DNA evidence and expressing confidence in the conclusions reached.