Single nucleotide polymorphism (SNP)

Forensic Biology Research and Development at NIJ

Forensic Biology involves the collection, study, and analysis of biological material on evidence from crime scenes to provide unbiased, scientific reports for a criminal or civil court case to give a better understanding of the crime that occurred. Historically, one of the earliest forensic biologists was Sir Alec Jeffreys in 1985 using DNA fingerprinting or DNA typing to individually identify humans.[1] He targeted variable...

Skater: An R Package for SNP-based Kinship Analysis, Testing, and Evaluation

Date Published

January 2022

Publication Type

Research (Applied/Empirical)

Agencies

NIJ-Sponsored

Massively Parallel Mitogenome Sequencing: Building a Strong Foundation for the Interpretation of MPS MtDNA

DJO-NIJ-22-RO-0005

Open

Funding First Awarded

2021

$624,692

Nuclear, Chloroplast, and Mitochondrial Data of a US Cannabis DNA Database

Date Published

2018

Publication Type

Research (Applied/Empirical), Report (Study/Research), Report (Grant Sponsored), Program/Project Description

Agencies

NIJ-Sponsored

Proteomic Genotyping of Fingermark Donors With Genetically Variant Peptides

Date Published

September 2019

Publication Type

Research (Applied/Empirical), Report (Study/Research), Report (Grant Sponsored), Program/Project Description

Agencies

NIJ-Sponsored

Six NSCL/P Loci Show Associations With Normal-Range Craniofacial Variation

Date Published

2018

Publication Type

Research (Applied/Empirical), Report (Study/Research), Report (Grant Sponsored), Program/Project Description

Agencies

NIJ-Sponsored

Proteomic genotyping: Using mass spectrometry to infer SNP genotypes in a forensic context

Date Published

December 2019

Agencies

NIJ-Sponsored

Demonstration of a mitochondrial DNA-compatible workflow for genetically variant peptide identification from human hair samples

Date Published

2019

Agencies

NIJ-Sponsored

Development of NGS (next generation sequencing) nomenclature framework

2016-DNR-6150

Closed

Funding First Awarded

2016

$748,000

Persistence of Touch DNA for Forensic Analysis

DJO-NIJ-19-RO-0002-1

Closed

Funding First Awarded

2018

$649,938

Microhaplotypes: A Comprehensive Forensic DNA Marker

Event Dates

June 22, 2021, 1:00 pm – 2:00 pm Eastern

Location

Online

Event Type

Webinar

Registration Status

Open

Effective Strategies for Forensic Analysis in the Mitochondrial DNA Coding Region

Date Published

2006

Publication Type

Report (Study/Research)

Agencies

NIJ-Sponsored

Developing a SNP Panel for Forensic Identification of Individuals

Date Published

2006

Publication Type

Report (Study/Research)

Agencies

NIJ-Sponsored

Sub-Populations Within the Major European and African Derived Haplogroups R1b3 and E3a are Differentiated by Previously Phylogenetically Undefined Y-SNPs

Date Published

2007

Publication Type

Report (Study/Research)

Agencies

NIJ-Sponsored

Recent Developments in Y-short Tandem Repeat and Y-single Nucleotide Polymorphism Analysis

Date Published

July 2003

Publication Type

Literature Review, Issue Overview

Agencies

NIJ-Sponsored

Highly Multiplexed Assays for Measuring Polymorphisms on the Y-chromosome

Date Published

2003

Publication Type

Report (Study/Research)

Agencies

NIJ-Sponsored

Improved Analysis of DNA Short Tandem Repeats With Time-of-Flight Mass Spectrometry

Date Published

October 2001

Publication Type

Research (Applied/Empirical)

Agencies

NIJ

Minimal SNP Overlap Among Multiple Panels of Ancestry informative Markers Argues for More International Collaboration

Date Published

July 2016

Publication Type

Research (Applied/Empirical), Report (Study/Research), Report (Grant Sponsored), Program/Project Description

Agencies

NIJ-Sponsored

Characterization of mtDNA SNP Typing and Mixture Ratio Assessment With Simultaneous Real-Time PCR Quantification of Both Allelic States

Date Published

2006

Publication Type

Report (Study/Research)

Agencies

NIJ-Sponsored

New Methods for Next-Generation Sequencing Analysis of Damaged and Mixed DNA Samples

Analysis of DNA From Post-blast Pipe Bomb Fragments for Identification and Determination of Ancestry

Date Published

January 2019

Agencies

NIJ-Sponsored

Embracing Next Generation Methods for Forensic DNA Sequence Analysis

Personal Identification and Ancestral Characterization from Genetically Variant Peptides in Human Hair

2019-R2-CX-0051

Closed

Funding First Awarded

2019

$50,000

Developing a Global Genotype Database to Predict Eye, Hair, and Skin Color from DNA

Katherine Gettings

Staff Scientist; NIJ Graduate Research Fellow