NCJ Number
231046
Journal
Techbeat Dated: Spring 2010
Date Published
May 2010
Length
2 pages
Annotation
This paper describes the innovative denaturing high-performance liquid chromatography (DHPLC) method for profiling DNA.
Abstract
After years of research, the denaturing high-performance liquid chromatography (DHPLC) originally developed as a biomedical technology for medical applications was adapted to forensic application. DHPLC allows for the rapid and accurate separation of mixtures that contain the mitochondrial DNA (mtDNA) of more than one person. The DHPLC method has the potential to benefit criminal and mass disaster investigations requiring timely analysis of mtDNA. This paper describes two major forensic applications for DHPLC in expediting mtDNA processing. The first application is comparative sequence analysis, and the second application of DHPLC application is the ability to separate mixtures that contain the mtDNA of more than one person.
Date Published: May 1, 2010
Downloads
Similar Publications
- Restoring Promise: Positive Research Results from a Program that Aims to Transform Correctional Culture
- Perceptions of School Climate Among Subgroups of Aggressive and Victimized Youth
- Forensic Science and the Courts - The Uses and Effects of Scientific Evidence in Criminal Case Processing - Final Report