Effects of obesity on talar micro- and macro-morphology

• NCJ Number: 307000
• Journal: Journal of Forensic Sciences Volume: 68 Issue: 2 Dated: 2023 Pages: 369-381
• Author(s): Adam D. Sylvester; Daniel J. Wescott; Deborah L. Cunningham; Devora S. Gleiber
• Date Published: March 2023
• Length: 13 pages
• Grant Number(s): 2020-R2-CX-0048
• Agencies: NIJ-Sponsored
• Publication Type: Research (Applied/Empirical)
• Award: Body mass estimation using bone micro- and macro-structure: a practical approach using CT imaging and computer analysis

Annotation

This article presents research into the use of obesity characteristics in the identification of human skeletal remains, specifically developing a forensic anthropological biological profile and documenting differences in talar shape and trabecular bone structure in obese and non-obese individuals.

Abstract

The addition of information regarding obesity status to the forensic anthropological biological profile could significantly contribute to the identification of human skeletal remains since over 40% of the U.S. adult population is currently obese. This study examines the differences in talar shape and trabecular bone structure between obese and non-obese individuals. A sample of 20 obese and 20 non-obese divided evenly by sex was selected from the Texas State University Donated Skeletal Collection. Tali were imaged using x-ray computed tomography (voxel size: 28–38.7 μm). Image stacks were processed to produce binary images as well as trabecular thickness and spacing maps. Landmark-based geometric morphometric analyses were conducted to quantify shape variation. Shape coordinates were used to locate 100 geometrically homologous volumes of interest within each talus. Bone volume fraction, trabecular thickness, and trabecular spacing were extracted at each volume of interest. Within each sex, a one-way ANCOVA was used to determine if significant differences exist between obese and non-obese individuals in trabecular bone after controlling for age. The size of the talus as well as subtle aspects of shape were found to distinguish the sexes. The results further indicate that bone volume fraction significantly differs between obese and non-obese males. In females, bone volume fraction is correlated with age but does not differ between obese and non-obese. The study demonstrates that bone microstructure is a promising approach to estimating body mass or body mass index category but age effects diminish the potential for the talus to be used alone. (Published Abstract Provided)