Comment on "DNA Mixtures Interpretation - A Proof-of-Concept Multi-Software Comparison Highlighting Different Probabilistic Methods' Performances on Challenging Samples" by Alladio et al

• NCJ Number: 254069
• Author(s): Duncan A. Taylor; John S. Buckleton; Jo-Anne Bright
• Date Published: 2019
• Length: 4 pages
• Grant Number(s): 2017-DN-BX-K541
• Agencies: NIJ-Sponsored
• Publication Type: Research (Applied/Empirical); Report (Study/Research); Report (Grant Sponsored); Program/Project Description

Annotation

This article comments on the recent publication by Alladio et al. of findings that compare the performance of semi-continuous probabilistic genotyping (PG) systems LRmix Studio and Lab Retriever, with the fully-continuous systems STRmix, EuroForMix, and DNA VIEW.

Abstract

Although there has been some previous work in this area, the breadth of samples tested and software compared have been limited. Alladio et al. fills a gap in the PG research landscape, which is the independent (in terms of software developers) comparison of the performance of such systems. This is one of the recommended actions for the field of DNA analysis by the PCAST report. (publisher abstract modified)