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Topic: Drugs,
Subtopic: Drugs

Identification and Quantification of New Psychoactive Substances Without Authentic Reference Standards

July 2025

This recording one of a group of presentations on The Synthetic Drug Crisis – Identifying NPS in Forensic Casework, which is session I in Best Practices Guidance for Advancing Research Initiatives and Combatting the Synthetic Drug Epidemic Online Workshop Series.

The workshop was presented by the NIJ Forensic Technology Center of Excellence on July 25, 2018.

Seized Drugs & Toxicology, 2025 NIJ Forensic Research and Development Symposium

February 2025

The Forensic Technology Center of Excellence assisted the National Institute of Justice in hosting the annual NIJ Forensic Science Research and Development Symposium on Tuesday, February 18, 2025 at the 77th Annual American Academy of Forensic Sciences meeting in Baltimore, Maryland. This video is one of five recorded sessions from the event. 

Presentations include -

Improving Consistency in Forensic Reporting Through DEA’s GUARDS Comprehensive Methodology

December 2024

This workshop explores the impact inconsistent drug analysis reporting has on public health and public trust. The value and implementation of the Global Uniform Analysis and Reporting of Drug-Related Substances (GUARDS) innovative methodology in over 200 instruments across United States Drug Enforcement Administration (DEA) laboratories are presented, as well as the efforts of other labs of the U.S. Customs and Border Protection (CBP) and Illinois State Police.

MDI Myth: Rapid Toxicology Screening Tools Can Replace Traditional

October 2024

This session busts the myth that new toxicology screening tools can fully replace traditional toxicology testing. The session discusses the appropriate integration of current rapid toxicology screening tools into MEC offices as a method of triaging cases, rather than a determination of toxicology related causes of deaths.

Evaluating a Statistical Method for Comparison of Mass Spectra of Novel Psychoactive Substance

July 2024

Identification of novel psychoactive substances (NPS) based on comparisons of electron-ionization (EI) mass spectra continues to pose challenges in seized drug analysis. In this webinar, a method to statistically compare EI mass spectra is described, and an application of the method to distinguish several structural and positional isomers of NPS analogs are demonstrated.

This webinar was hosted by the NIJ Forensic Technology Center of Excellence on July 25, 2024. 

Just Navigating Reentry using Peer Support

July 2024

In episode five of our community based solutions for Substance Use Challenges season Just Science sits down with doctor Nicole Swiderski, New Jersey path to recovery grant manager and Jass Pelland, New Jersey Path to Recovery program manager to discuss how the New Jersey State Parole Board's 2021 Comprehensive Opioid Stimulant and Substance Use Program Award is supporting peer recovery and other services that help individuals with a substance use disorder navigate reentering the community after release from prison.

Just Increasing Access To Drug - Checking Services

July 2024

In episode four of our community based solutions for Substance Use Challenges season, Just Science sits down with Doctor Nabarun Dasgupta, pharmacoepidemiologist and senior scientist at the University of North Carolina Injury Prevention Research Center, and Erin Tracy, research chemist in the University of North Carolina Injury Prevention Research Center, to discuss their unique approach to providing drug checking services on a broad scale.

Just Wastewater Drug Surveillance in Kentucky

July 2024

In episode three of our Community Based solutions for Substance Use Challenges season, Just Science sits down with Doctor Chris Delcher, associate professor in the Department of Pharmacy Practice and Science and director of the Institute for Pharmaceutical Outcomes and Policy at the University of Kentucky, to discuss how his team tracks community drug use through wastewater analysis. Much like analyzing a urine sample to determine what drugs an individual is using. Analyzing wastewater from a community offers insight into drug trends across an entire region of people.

Quantitative Analysis Method For Tetrahydrocannabinol Isomers

June 2024

Of recent, forensic toxicology laboratories have been grappling with the emergence of tetrahydrocannabinol isomers within biological specimens. Traditional methodologies are often inadequate in the separation of Δ9-tetrahydrocannabinol and Δ8-tetrahydrocannabinol, which are the most common isomers identified in forensic testing.

Just Improving Forensic Toxicology Testing in DC

June 2024

In episode one of our Community Based Solutions for Substance Use Challenges season just sat down with Doctor Samantha Tolliver, Chief Toxicologist for the District of Columbia Office of the Chief Medical Examiner, or DC OCME, to discuss how their agency uses their Bureau of Justice Assistances Comprehensive Opioid Stimulant and Substance Use Program, or COSSUP, funding to improve their drug testing and analysis processes.

Audio file

What's Known and Unknown about Marijuana, Part 2

January 2024

Marijuana legalization poses many challenges — especially those related to drug chemistry and toxicology — for researchers, law enforcement, and policy makers. In the latest episode of Justice Today, NIJ Communications Assistant Josh Mondoro hosts a conversation with NIJ Scientist Frances Scott about marijuana toxicology, including comparing its effects to alcohol, measuring impairment, and maintaining public safety as more and more states legalize recreational marijuana. 

What's Known and Unknown about Marijuana, Part 1

January 2024

Marijuana poses many challenges for researchers, law enforcement, and policy makers, challenges that fall into two fields: drug chemistry and toxicology. NIJ scientist Dr. Frances Scott joins this episode to explain the complications in drug chemistry and how difficulties defining marijuana lead to backlogs in crime labs around the country. NIJ Communications Assistant Josh Mondoro hosts. 

A Data-Informed Response to Emerging Drugs

December 2023

The emerging drug crisis in the U.S. touches both criminal justice and public health, and experts from both fields came together at NIJ’s 2023 National Research Conference to discuss strategies and tools to fight this problem. Dr. Frances Scott, NIJ scientist and program manager, continues the conference discussion with two fellow panelists: Ciena Bayard, the Method Development and Validation Program Manager for D.C. Office of the Chief Medical Examiner, and Haley Greene, the Deputy Epidemiologist for the Central Region for the Virginia Department of Health. Read the transcript.

Cannabinoid Conundrums Webinar Series Expert Panel

August 2023

As evident by the Cannabinoid Conundrums webinar series, the rapidly changing world of cannabinoids offers many conundrums. To tackle some of these questions, Dr. Ruth Winecker led a panel discussion with Dr. Ed Cone, Dr. Nathalie Desrosiers, Mr. Justin Poklis, and Mr. Nelson Santos. This diverse slate of thought leaders includes experts in analytical chemistry, forensic toxicology, clinical research, and drug chemistry. This webinar was hosted by the NIJ Forensic Technology Center of Excellence on August 3, 2023. 

Cannabinoid Pharmacology: Three Decades of Controlled Human Cannabinoid

August 2023

Controlled drug administration studies are valuable tools for acquiring a detailed understanding of the pharmacodynamic and pharmacokinetic profiles of cannabinoids. ∆9-tetrahydrocannabinoid (THC) is the primary psychoactive cannabinoid in cannabis with the potential to negatively impact cognitive and psychomotor performance and workplace safety. These studies establish behavioral and subjective effect profiles while simultaneously collecting pharmacokinetics data.

Vaping in the Weeds: The Merging of the E-cigarette and Cannabis Industries

June 2023

This presentation describes the nature of the merge of the e-cigarette and cannabis industries. Quality assurance issues as a result of the absence of regulation and oversight is described. Cases of self-reported adverse events and the challenges of cannabis product analysis are also discussed.

This webinar was hosted by the NIJ Forensic Technology Center of Excellence on June 29, 2023. 

Development of Analytical Methods for Measuring Δ9 THC in Cannabis Products

June 2023

With the passage of the 2018 Agricultural Improvement Act (Farm Bill), forensic laboratories have been tasked with differentiating seized cannabis samples as either hemp or marijuana. The new legislation declassified hemp as a Schedule 1 drug substance and defined it as cannabis containing 0.3 % or less of decarboxylated-Δ9-THC (total Δ9-THC). The National Institute of Standards and Technology (NIST) has been working to help forensic laboratories with these challenging measurements through the development of extraction protocols and analytical methods.

All Is Not Pot That’s Green: An Overview of THC Isomers

June 2023

THC isomers, also known as THC analogs or semi-synthetic cannabinoids, are structurally related to Δ9-tetrahydrocannabinol (Δ9-THC) and have similar toxicity and impairing effects. A recent study indicated that Δ8-THC use was around 27% of marijuana use, based on detection and ratios of cannabinoid metabolites in workplace drug testing. Other analogs of interest include hexahydrocannabinol (HHC) and THC-O. THC isomers are generally perceived as legal and are also seen in states with legal marijuana.

Vaping: It's Not What You Think

May 2023
Vaping has grown in popularity as an alternative to cigarettes, but like its predecessor, vaping brings many health complications to consumers. Thanks to the persistence of researchers like Dr. Michelle Peace, these once unknown dangers have been brought to light. Dr. Peace, a tenured Associate Professor and founding member of VCU’s Department of Forensic Science, joins host and NIJ Scientist Dr. Frances Scott to discuss the history and science of vaping and what it does to our bodies.

Just Rapidly Identifying Drugs Involved In Suspected Overdoses

April 2023

In episode two of our Community-based Solutions for Substance Use Challenges season, Just Science sits down with Bill Barbour, Fatal Overdose Surveillance Program Manager at King County Medical Examiner’s Office, to discuss his team’s methods for rapid toxicology results after a suspected overdose death.

Labeling with Love or Lethal Consequences for CBD Containing Products

March 2023

The reauthorization of hemp due to the Agriculture Improvement Act of 2018 (Farm Bill) has caused a proliferation of products that contain cannabidiol (CBD). While CBD is considered ‘legal’ under the Farm-Bill, there are concerns that the labeling of CBD products is inaccurate, and that the products may contain other cannabinoids, including Δ9-tetrahydrocannabinol (THC), the main psychoactive compound in marijuana. Other concerns include the potential for conversion of CBD to other cannabinoids during analysis of biological matrices and in acidic foods and beverages.