All Is Not Pot That’s Green: An Overview of THC Isomers
THC isomers, also known as THC analogs or semi-synthetic cannabinoids, are structurally related to Δ9-tetrahydrocannabinol (Δ9-THC) and have similar toxicity and impairing effects. A recent study indicated that Δ8-THC use was around 27% of marijuana use, based on detection and ratios of cannabinoid metabolites in workplace drug testing. Other analogs of interest include hexahydrocannabinol (HHC) and THC-O. THC isomers are generally perceived as legal and are also seen in states with legal marijuana. Analytical challenges include differentiating THC isomers from each other and Δ9-THC and avoiding conversion during sample preparation.
This webinar was hosted by the NIJ Forensic Technology Center of Excellence on June 15, 2023.
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