Description of original award (Fiscal Year 2010, $1,351,352)
Single nucleotide polymorphism (SNP) panels can be used for inference of ancestry, phenotypic information (i.e. physical appearance), and individual human identification. Previous work has contributed to a database of Ancestry Informative SNPs (AISNPs) that is already able to provide reasonable probabilities of assignment of an individual to one of nearly a dozen regions of the world. In this application researchers propose to strengthen and extend the study beyond the current set of 44 populations to a minimum of 57 populations. Researchers also propose to include potentially phenotype informative SNPs (PISNPs) in the population studies and focus on development of Lineage Informative markers (LISNPs) which are DNA polymorphism panels with high probability of identifying membership in an extended family).