The development of microfluidic devices for the rapid isolation and detection of drugs of abuse.

The goal of this proposal is to further develop technologies for rapid analysis of drugs of abuse using microfluidic systems. A range of drugs in various matrices will be targeted, including those implicated in drug-facilitated sexual assault. In previous phases of this work, the principal investigator developed a rapid screening method for the simultaneous detection of two classes of date-rape drugs, with separation in under 16 minutes. Derivatization techniques and generic detection schemes will be explored to enable screening of a wide range of drugs. nca/ncf