Novel psychoactive substances

Implementation of NPS Discovery – An Early Warning Systems for Novel Drug Intelligence, Surveillance, Monitoring, Response, and Forecasting using Drug Materials and Toxicology Populations in the US

15PNIJ-22-GG-04434-MUMU

Past Project Period End Date

Funding First Awarded

2023

$492,810

Potency Testing of up to Sixteen Cannabinoids in Hemp-infused Edibles using Liquid Chromatography Diode Array Detector with Optional Confirmation of Identity by Electrospray Ionization Time-of-flight Mass Spectrometry

Date Published

August 2023

Publication Type

Research (Applied/Empirical)

Agencies

NIJ-Sponsored

Identifying reliable ions for the statistical differentiation of structurally similar fentanyl analogs

Date Published

2023

Agencies

NIJ-Sponsored

Synthetic Stimulant Market Rapidly Changing as N,N-Dimethylpentylone Replaces Eutylone in Drug Supply Typically Sold as “Ecstasy” or “Molly”

Date Published

2022

Agencies

NIJ-Sponsored

NPS Discovery Q2 2023 Trend Reports

Date Published

2023

Agencies

NIJ-Sponsored

New Potent Synthetic Opioid—N-Desethyl Isotonitazene—Proliferating Among Recreational Drug Supply in USA

Date Published

2023

Publication Type

Research (Applied/Empirical)

Agencies

NIJ-Sponsored

N,N-Dimethylpentylone (NPS Stimulant)

Date Published

2022

Publication Type

Research (Applied/Empirical)

Agencies

NIJ-Sponsored

Positivity of New Synthetic Cannabinoid 4F-MDMB-BICA Increasing in U.S. as Prevalence of 5F-MDMB-PICA Wanes

Date Published

2023

Agencies

NIJ-Sponsored

N-Pyrrolidino Etonitazene (NPS Opioid)

Date Published

2022

Agencies

NIJ-Sponsored

N,N-Dimethylpentylone (dipentylone)—A new synthetic cathinone identified in a postmortem forensic toxicology case series

Date Published

June 2023

Agencies

NIJ-Sponsored

Metonitazene Begins Proliferation as Newest Synthetic Opioid Among Latest Cycle of Non-Fentanyl Related Drugs

Date Published

2021

Agencies

NIJ-Sponsored

Etodesnitazene — New Synthetic Opioid Identified During Forensic Death Investigations in the United States and Canada

Date Published

2021

Agencies

NIJ-Sponsored

Bromazolam Prevalence Surging Across the United States Driven In Part by Increasing Detections Alongside Fentanyl

Date Published

2022

Agencies

NIJ-Sponsored

Assessment of the Contribution to Drug Impaired Driving from Emerging and Undertested Drugs

Date Published

2023

Publication Type

Research (Applied/Empirical)

Agencies

NIJ-Sponsored

Gas chromatography/mass spectrometry analysis of the six-ring regioisomeric dimethoxybenzyl-N-methylpiperazines (DMBMPs)

Date Published

2013

Publication Type

Research (Applied/Empirical)

Agencies

NIJ-Sponsored

A Strategy to Prioritize Emerging Drugs of Abuse for Analysis: Abuse Liability Testing Using Intracranial Self-stimulation (ICSS) in Rats and Validation with α-pyrrolidinohexanophenone (α-PHP)

Date Published

2021

Publication Type

Research (Applied/Empirical)

Agencies

NIJ-Sponsored

Creation and Release of an Updated NIST DART-MS Forensics Database

Date Published

February 2021

Publication Type

Research (Applied/Empirical)

Agencies

NIJ-Sponsored

Prevalence of Novel Psychoactive Substances in Oral Fluid, Final Research Report

Date Published

December 2021

Agencies

NIJ-Sponsored

Chemometric Processing of DART-HRMS-derived Dark Matter for the Identification of New Psychoactive Substances

Date Published

March 2021

Agencies

NIJ-Sponsored

To Catch a Drug

Date Published

October 2022

Publication Type

Research (Applied/Empirical)

Agencies

NIJ

NIJ communications assistant Josh Mondoro explores novel psychoactive substances with NIJ scientist Frances Scott. She explains what NPSs are, current research in the field, and the practical impact of this research for law enforcement and policymakers.

Implementation of NPS Discovery – An Early Warning Systems for Novel Drug Intelligence, Surveillance, Monitoring, Response, and Forecasting using Drug Materials and Toxicology Populations in the US

15PNIJ-22-GG-04434-MUMU

Past Project Period End Date

Funding First Awarded

2022

$485,938

Real-Time Sample-Mining and Data-Mining Approaches for the Discovery of Novel Psychoactive Substances (NPS)

2020-DQ-BX-0007

Past Project Period End Date

Funding First Awarded

2022

$200,000

Rapid determination of the 'legal highs' 4MMC and 4MEC by spectroelectrochemistry: simultaneous cyclic voltammetry and in situ surface-enhanced Raman spectroscopy

Date Published

2021

Publication Type

Research (Applied/Empirical)

Agencies

NIJ-Sponsored

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Implementation of NPS Discovery – An Early Warning Systems for Novel Drug Intelligence, Surveillance, Monitoring, Response, and Forecasting using Drug Materials and Toxicology Populations in the US

Potency Testing of up to Sixteen Cannabinoids in Hemp-infused Edibles using Liquid Chromatography Diode Array Detector with Optional Confirmation of Identity by Electrospray Ionization Time-of-flight Mass Spectrometry

Identifying reliable ions for the statistical differentiation of structurally similar fentanyl analogs

Synthetic Stimulant Market Rapidly Changing as N,N-Dimethylpentylone Replaces Eutylone in Drug Supply Typically Sold as “Ecstasy” or “Molly”

NPS Discovery Q2 2023 Trend Reports

New Potent Synthetic Opioid—N-Desethyl Isotonitazene—Proliferating Among Recreational Drug Supply in USA

N,N-Dimethylpentylone (NPS Stimulant)

Positivity of New Synthetic Cannabinoid 4F-MDMB-BICA Increasing in U.S. as Prevalence of 5F-MDMB-PICA Wanes

N-Pyrrolidino Etonitazene (NPS Opioid)

N,N-Dimethylpentylone (dipentylone)—A new synthetic cathinone identified in a postmortem forensic toxicology case series

Metonitazene Begins Proliferation as Newest Synthetic Opioid Among Latest Cycle of Non-Fentanyl Related Drugs

Metonitazene (NPS Opioid)

Etodesnitazene — New Synthetic Opioid Identified During Forensic Death Investigations in the United States and Canada

Bromazolam Prevalence Surging Across the United States Driven In Part by Increasing Detections Alongside Fentanyl

Assessment of the Contribution to Drug Impaired Driving from Emerging and Undertested Drugs

Gas chromatography/mass spectrometry analysis of the six-ring regioisomeric dimethoxybenzyl-N-methylpiperazines (DMBMPs)

A Strategy to Prioritize Emerging Drugs of Abuse for Analysis: Abuse Liability Testing Using Intracranial Self-stimulation (ICSS) in Rats and Validation with α-pyrrolidinohexanophenone (α-PHP)

Creation and Release of an Updated NIST DART-MS Forensics Database

Prevalence of Novel Psychoactive Substances in Oral Fluid, Final Research Report

Chemometric Processing of DART-HRMS-derived Dark Matter for the Identification of New Psychoactive Substances

To Catch a Drug

To Catch a Drug

Implementation of NPS Discovery – An Early Warning Systems for Novel Drug Intelligence, Surveillance, Monitoring, Response, and Forecasting using Drug Materials and Toxicology Populations in the US

Real-Time Sample-Mining and Data-Mining Approaches for the Discovery of Novel Psychoactive Substances (NPS)

Rapid determination of the 'legal highs' 4MMC and 4MEC by spectroelectrochemistry: simultaneous cyclic voltammetry and in situ surface-enhanced Raman spectroscopy

Novel psychoactive substances

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