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A template for the validation of DART-MS for qualitative seized drugs analysis

NCJ Number
Forensic Chemistry Volume: 29 Dated: July 2022
Date Published
July 2022

To provide additional resources to assist in validation development, this paper provides a template that can be adopted or adapted for implementation of DART-MS, or other ambient ionization mass spectrometry techniques, for qualitative seized drug analysis.


Direct analysis in real time mass spectrometry (DART-MS) is an increasingly employed tool for a wide range of forensic applications, including seized drug analysis. A significant body of research surrounds DART-MS for the analysis of seized drugs and how it can be used to address many of the challenges caused by the increased presence of emerging drugs and novel psychoactive substances. A lack of available resources to help address validation, operation, training, and data interpretation needs is just one of the hurdles that laboratories face when adopting new technologies, such as DART-MS. (Publisher abstract provided)


Date Published: July 1, 2022