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Mass spectrometry

Virtual Workshop Series: Direct Analysis in Real Time Mass Spectrometry (DART-MS) for Seized Drug Analysis

Direct Analysis in Real Time Mass Spectrometry (DART-MS) is a powerful analytical technique that allows for rapid detection and characterization of a wide range of compounds, including seized drugs. Over the last ten years, the DART- MS has slowly gained in popularity in crime labs due to its ability to provide rapid, reliable results with minimal samples preparation. Despite these advantages, DART-MS remains underutilized due to cost, data interpretation...

TOF/QTOF Mass Spec for Identification, Screening & Confirmation in Forensic Toxicology & Chemistry, Part II

October 2023

In this specialized workshop intended for forensic science service providers (FSSPs), we explore the increasing adoption of Time-of-Flight and Quadrupole Time-of-Flight Mass Spectrometry (TOF/QTOF-MS) technologies within forensic laboratories. The session provides an in-depth examination of various critical stages, encompassing planning, validation methodologies, analytical techniques, data review processes, and report generation. Subject matter experts disseminate knowledge and share first-hand experiences related to the utilization of TOF/QTOF-MS technology.

TOF/QTOF Mass Spec for Identification, Screening & Confirmation in Forensic Toxicology & Chemistry, Part I

October 2023

In this specialized workshop intended for forensic science service providers (FSSPs), we explore the increasing adoption of Time-of-Flight and Quadrupole Time-of-Flight Mass Spectrometry (TOF/QTOF-MS) technologies within forensic laboratories. The session provides an in-depth examination of various critical stages, encompassing planning, validation methodologies, analytical techniques, data review processes, and report generation. Subject matter experts disseminate knowledge and share first-hand experiences related to the utilization of TOF/QTOF-MS technology.

Validation of a Confirmatory Proteomic Mass Spectrometry Body Fluid Assay

December 2023

While forensic DNA analysis can identify an individual(s) at a crime scene, it cannot identify the biological source from which that DNA was obtained – e.g. blood, saliva, or semen. Identification of the biological source of DNA can provide important contextual information for forensic investigations as well as evidence in court. Nearly all current methods used for body fluid identification are presumptive. Here we present a new proteomic mass spectrometry method for the confirmatory identification of blood, saliva, and semen.