In this Review, we explore microbial succession in the healthy human microbiota from the cradle to the grave.
We discuss the stages from primary succession at birth, to disruptions by disease or antibiotic use, to microbial expansion at death. We address how these successions differ by body site and by domain (bacteria, fungi or viruses). We also review experimental tools that microbiota researchers use to conduct this work. Finally, we discuss future directions for studying the microbiota’s relationship with age, including designing consistent, well-powered, longitudinal studies, performing robust statistical analyses and improving characterization of non-bacterial microorganisms. (Publisher abstract provided)
Downloads
Similar Publications
- Sampling from four geographically divergent young female populations demonstrates forensic geolocation potential in microbiomes
- The Sentinel Role of Forensic Toxicology Laboratories to Identify and Act Upon Diverse Drug Threats by Addressing Toxicology and Economic Demands
- Romantic Relationship Characteristics and Adolescent Relationship Abuse in a Probability-Based Sample of Youth