Meta-Analysis of Genome-wide Association Studies Identifies 8 Novel Loci Involved in Shape Variation of Human Head Hair

• NCJ Number: 253314
• Journal: Human Molecular Genetics Volume: 27 Issue: 3 Dated: February 2018 Pages: 559-575
• Author(s): Fan Liu; Yan Chen; Gu Zhu; Pirro G. Hysi; Sijie Wu; Kaustubh Adhikari; Krystal Breslin; Ewelina Pospiech; Merel A. Hamer; Fuduan Peng
• Date Published: February 2018
• Length: 17 pages
• Grant Number(s): 2014-DN-BX-K031
• Agencies: NIJ-Sponsored
• Publication Type: Research (Applied/Empirical)
• Award: Improving the prediction of human quantitative pigmentation traits such as eye, hair and skin color using a worldwide representation panel of US and European individuals

Annotation

Since shape variation of human head hair shows striking variation within and between human populations, although its genetic basis is far from being understood, the current study performed a series of genome-wide association studies (GWASs) and replication studies in a total of 28,964 subjects from 9 cohorts with multiple geographic origins.

Abstract

Since shape variation of human head hair shows striking variation within and between human populations, although its genetic basis is far from being understood, the current study performed a series of genome-wide association studies (GWASs) and replication studies in a total of 28,964 subjects from 9 cohorts with multiple geographic origins. (publisher abstract modified)