This article reports on a study that compared the analytical properties of a series of cyclic tertiary aminoketones and the corresponding desoxy phenethylamines
The desoxy phenethylamine analogues in this study represent a combination of alkyl side-chain and cyclic amines (azetidine, pyrrolidine, piperidine and azepane) to yield a set of molecules of identical elemental composition as well as major mass spectral fragment ions (base peaks) of identical elemental composition. These desoxy phenethylamine analogues of the aminoketone designer drug, 3,4-methylenedioxy-pyrrovalerone (MDPV) related to the natural product cathinone were prepared from piperonal (3,4-methylenedioxybenzaldehyde) via the intermediate precursor ketones. The aminoketones and the desoxy phenethylamine regioisomers were each separated in capillary gas chromatography experiments using an Rxi-17Sil MS stationary phase with the aminoketones showing greater retention than the corresponding desoxyamines. (Publisher abstract modified)
Downloads
Similar Publications
- Trauma and Long-Term Memory for Childhood Events: Impact Matters
- A Systematic Study of Liquid Chromatography in Search of the Best Separation of Cannabinoids for Potency Testing of Hemp-Based Products Using Diode Array Detector and Electrospray Ionization Mass Spectrometry
- EVALUATING THE SUCCESS OF A KINETIC MODEL TO PREDICT CHROMATOGRAMS OF IGNITABLE LIQUIDS UNDER DIFFERENT EVAPORATION MODES AND IN THE PRESENCE OF PASSIVE-HEADSPACE EXTRACTION