Sample preparation is the most common bottleneck in the analysis and processing of forensic evidence. Time-consuming steps in many forensic tests involve complex separations, such as liquid and gas chromatography or various types of extraction techniques, typically coupled with mass spectrometry (e.g., LC-MS). Ambient ionization ameliorates these slow steps by reducing or even eliminating sample preparation. Although some ambient ionization techniques have been adopted by the forensic community, there is significant resistance to discarding chromatography, since most forensic analyses require both an identification and a confirmation technique. With the use of a paper substrate as described in this article, the same substrate can also act as the paper substrate for paper spray mass spectrometry. The coupling of SERS and paper spray ionization creates a quick, forensically feasible combination. (publisher abstract modified)
Downloads
Similar Publications
- Raman spectroscopic signature of vaginal fluid and its potential application in forensic body fluid identification
- The Cross-Reactivity of the Cannabinoid Analogs (delta-8-THC, delta-10-THC and CBD) and their metabolites in Urine of Six Commercially Available Homogeneous Immunoassays, Grant Report
- Helping Crime Victims - Levels of Trauma and Effectiveness of Services - Executive Summary