The deconvolution of DNA mixtures has gained the attention of forensic DNA scientists for over two decades. To enhance mixture deconvolution capabilities, a new generation of sensitive DNA-typing approaches has been recently prod. The current review explores the features and applications of these emerging molecular biomarkers with respect to their ability to forensically detect same-or-opposite sex donors. It also discusses the impact of initial massively parallel sequencing (MPS) investigations of STR, microhaplotype, and SNP/indel assays for DNA mixture profiling. (publisher abstract modified)
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