U.S. flag

An official website of the United States government, Department of Justice.

Democrats have shut down the government. Department of Justice websites are not currently regularly updated. Please refer to the Department of Justice’s contingency plan for more information.

Comparative Analysis of Two Different Sets of Y-Chromosome Short Tandem Repeats (Y-STRs) on a Common Population Panel

NCJ Number
229590
Journal
Forensic Science International: Genetics Volume: 4 Issue: 1 Dated: December 2009 Pages: 11-20
Date Published
December 2009
Length
10 pages
Annotation

A comparative analysis of two Y-STR loci sets was conducted on a population sample of 224 individuals, 114 Caucasians and 110 African-Americans.

Abstract

One set of loci, designated the OSU 10-locus set, comprises variable, single copy, male-specific loci that are dispersed across the Y-chromosome. Parallel evaluations were performed using the 10 Y-chromosome loci most frequently used for forensic analysis, the loci chosen as the SWGDAM Y-STR loci. The OSU 10-locus set had a greater average number of alleles per locus and higher average gene diversity than the SWGDAM loci. The OSU 10-locus set found 220 unique haplotypes in 224 individuals. In approximately 6000 pairwise haplotype comparisons for each population with each set of loci, the OSU 10-locus set also yielded a greater average number of allelic differences per pair than the SWGDAM loci. Finally, the overall linkage disequilibrium levels were lower for the OSU 10-locus set in the Caucasian population. In general, the OSU 10-locus set revealed a higher power of discrimination than the SWGDAM set. Tables, figures, appendix, and references (Published Abstract)

Date Published: December 1, 2009