52 Additional Reference Population Samples for the 55 AISNP Panel

• NCJ Number: 249960
• Journal: Forensic Science International: Genetics Volume: 19 Dated: November 2015 Pages: 269-271
• Author(s): A. J. Pakstis; E. Haigh; L. Cherni; A. B.A. Elgaaied; A. Barton; B. Evsanaa; A. Togtokh; J. Brissenden; J. Roscoe; O. Bulbul; G. Filoglu; C. Gurkan; K. A. Meiklejohn; J. M. Robertson; C. X. Li; Y. L. Wei; H. Li; U. Soundararajan; H. Rajeevan; J. R. Kidd; K. K. Kidd
• Date Published: November 2015
• Length: 3 pages
• Grant Number(s): 2013-DN-BX-K023; 2014-DN-BX-K030
• Agencies: NIJ-Sponsored
• Publication Type: Research (Applied/Empirical)
• Award: Continued Development of FROG-kb: A Forensic Resource/Reference on Genetics knowledge base; High resolution SNP panels for forensic identification of ancestry, family, and phenotype.

Annotation

This project added reference population allele frequencies for 52 population samples to the 73 previously entered, so that there are now allele frequencies publicly available in ALFRED and FROG-kb for a total of 125 population samples.

Abstract

Ancestry inference for a person using a panel of SNPs depends on the variation of frequencies of those SNPs around the world and the amount of reference data available for calculation/comparison. The Kidd Lab panel of 55 AISNPs has been incorporated in commercial kits by both Life Technologies and Illumina for massively parallel sequencing. Therefore, a larger set of reference populations will be useful for researchers using those kits. (Publisher abstract modified)