Description of original award (Fiscal Year 2007, $685,000)
MicroCantilever (MC) based sensors can provide revolutionary sensitivity for forensic detection and identification of controlled substances, toxic species, biological molecules and DNA matching. Current sensor systems require extensive sample preparation and/or specialized instrumentation to identify molecules of controlled substances such as cocaine with high specificity and sensitivity. Ames Laboratory aims to overcome these limitations by developing a novel sensing approach based on MC sensors coupled with aptamer-based receptor layers. In order to demonstrate the feasibility and forensic suitability of our approach, we will develop sensors for sensitive and specific identification of cocaine, cocaine metabolites and methamphetamine molecules.
- Establishing a National Firearms and Toolmark Statistical Background Population for Calculation of Error Rates
- Improving Evidence Management: Best Practices for Handling, Preservation, Retention, and Tracking
- Sex-Based Targeted Recovery of Cells in a Heterogeneous Mixture: Separating Male and Female Like Cells