Implementation of NPS Discovery – An Early Warning Systems for Novel Drug Intelligence, Surveillance, Monitoring, Response, and Forecasting using Drug Materials and Toxicology Populations in the US

Award Information

Awardee

THE FREDRIC RIEDERS FAMILY RENAISSANCE FOUNDATION

Award #

15PNIJ-22-GG-04434-MUMU

Funding Category

Competitive Discretionary

Location

HORSHAM, PA

Congressional District

Status

Past Project Period End Date

Funding First Awarded

2022

Total funding (to date)

$978,748

Original Funding Opportunity

NIJ FY22 Research and Development in Forensic Sciences for Criminal Justice Purposes

Grant-Funded Publications

Implementation of NPS Discovery – An Early Warning System for Novel Drug Intelligence, Surveillance, Monitoring, Response, and Forecasting using Drug Materials
Date Published: February 2026
Designer Fentanyl Precursors Leading the Way to New Fentanyl Analogs—The Case of ortho-Methylfentanyl
Journal: American Journal of Forensic Medicine and Pathology

Date Published: December 2025
Rapid LC–QTOF–MS screening method for semi-synthetic cannabinoids in whole blood
Journal: Journal of Analytical Toxicology

Date Published: October 2025
The Rapid Spread of a Novel Adulterant in the US Illicit Drug Supply—BTMPS
Journal: JAMA Internal Medicine

Date Published: July 2025
“Do It Yourself” Synthetic Cannabinoid Receptor Agonist Precursors as a Ban-Evading Strategy: Comparison of the Pharmacological Characteristics of Precursors and Their Final Products
Journal: Drug Testing and Analysis

Date Published: July 2025
New and Emerging “Nitazene” Analogues Appearing in Medicolegal Death Investigations
Journal: American Journal of Forensic Medicine and Pathology

Date Published: June 2025
Medetomidine quantitation and enantiomer differentiation in biological specimens collected after fatal and non-fatal opioid overdoses
Journal: Journal of Analytical Toxicology

Date Published: May 2025
Overdoses Involving Medetomidine Mixed with Opioids — Chicago, Illinois, May 2024
Date Published: May 2025
Tail-less precursors in synthetic cannabinoid production: investigating a clandestine laboratory, seized samples, and CB1 activity
Journal: Archives of Toxicology

Date Published: May 2025
Identification and Investigation of the Intrinsic Receptor Activation Potential and Metabolization of the New Oxo-Pyridyl Synthetic Cannabinoid Receptor Agonist CH-FUBBMPDORA
Journal: Drug Testing and Analysis

Date Published: February 2025
Clinical characteristics of patients exposed to medetomidine in the illicit opioid drug supply in Philadelphia – a case series
Journal: Clinical Toxicology

Date Published: 2025
Toxicological Evaluation, Postmortem Case Descriptions, and Pharmacological Activity of N,N-dimethylpentylone and Related Analogs
Journal: Journal of Analytical Toxicology

Date Published: January 2025
Identification and Health Risks of an Emerging Means of Drug Use in Correctional Facilities
Journal: JAMA Network Open

Date Published: December 2024
ortho-Methylfentanyl Proliferating Across North America As Newest Synthetic Opioid Identified in Fatal Drug Overdoses
Date Published: December 2024
Identification of ADB-5'Br-BINACA in Plant Material and Analytical Characterization Using GC-MS, LC-QTOF-MS, NMR and ATR-FTIR
Journal: Journal of Pharmaceutical and Biomedical Analysis

Date Published: September 2024
In Vitro Structure-activity Relationships and Forensic Case Series of Emerging 2-benzylbenzimidazole 'Nitazene' Opioids
Journal: Archives of Toxicology

Date Published: September 2024
Medetomidine Infiltrates the US Illicit Opioid Market
Journal: JAMA

Date Published: September 2024
2F-2oxo-PCE: A New Synthetic Hallucinogen Identified in Recreational Drug Markets Across North America
Date Published: May 2024
Workflow to Facilitate the Detection of New Psychoactive Substances and Drugs of Abuse in Influent Urban Wastewater
Journal: Journal of Hazardous Materials

Date Published: May 2024
Wastewater-based Monitoring of the Nitazene Analogues: First Detection of Protonitazene in Wastewater
Journal: Science of the Total Environment

Date Published: April 2024
Evaluating Cross-reactivity of New Psychoactive Substances (NPS) in Human Whole Blood by Enzyme-linked Immunosorbent Assay (ELISA)
Journal: Journal of Analytical Toxicology

Date Published: March 2024
Notes from the Field: Cluster of Severe Illness from Neptune’s Fix Tianeptine Linked to Synthetic Cannabinoids — New Jersey, June–November 2023
Journal: Morbidity and Mortality Weekly Report

Date Published: February 2024
Medetomidine Rapidly Proliferating Across USA — Implicated In Recreational Opioid Drug Supply & Causing Overdose Outbreaks
Date Published: 2024
Fighting the Uphill War Against Illicit Drugs and Overdose Deaths: Detecting Emerging Designer Drugs and Opioid Analogs
Date Published: September 2023
New Nitazene Analogue N-Pyrrolidino Protonitazene Impacting Drug Markets In North America and Europe
Date Published: August 2023
NPS Discovery Q2 2023 Trend Reports
Date Published: 2023

Date Created: September 30, 2022

Implementation of NPS Discovery – An Early Warning Systems for Novel Drug Intelligence, Surveillance, Monitoring, Response, and Forecasting using Drug Materials and Toxicology Populations in the US

Note:

Award Information

Similar Awards

Implementation of NPS Discovery – An Early Warning Systems for Novel Drug Intelligence, Surveillance, Monitoring, Response, and Forecasting using Drug Materials and Toxicology Populations in the US

Award Information

Supplemental Award 1 (Fiscal Year 2023, $492,810)

Grant-Funded Publications

Similar Awards