Degraded DNA samples

A Comparison of the Effects of PCR Inhibition in Quantitative PCR and Forensic STR Analysis

Date Published

2011

Publication Type

Research (Applied/Empirical), Report (Study/Research), Report (Grant Sponsored), Program/Project Description

Agencies

NIJ-Sponsored

Recovery of Whole Mitochondrial Genome From Compromised Samples via Multiplex PCR and Massively Parallel Sequencing

Date Published

2018

Publication Type

Research (Applied/Empirical), Report (Study/Research), Report (Grant Sponsored), Program/Project Description

Agencies

NIJ-Sponsored

Assessment of Impact of DNA Extraction Methods on Analysis of Human Remain Samples on Massively Parallel Sequencing Success

Date Published

January 2019

Publication Type

Research (Applied/Empirical), Report (Study/Research), Report (Grant Sponsored), Program/Project Description

Agencies

NIJ-Sponsored

Impact of DNA Degradation on Massively Parallel Sequencing-based Autosomal STR, iiSNP, and Mitochondrial DNA Typing Systems

Date Published

2019

Publication Type

Research (Applied/Empirical), Report (Study/Research), Report (Grant Sponsored), Program/Project Description

Agencies

NIJ-Sponsored

Evaluation of Mitogenome Sequence Concordance, Heteroplasmy Detection, and Haplogrouping in a Worldwide Lineage Study Using the Precision ID mtDNA Whole Genome Panel

Date Published

September 2019

Publication Type

Research (Applied/Empirical), Report (Study/Research), Report (Grant Sponsored), Program/Project Description

Agencies

NIJ-Sponsored

The Stability and Persistence of Blood and Semen mRNA and miRNA Targets for Body Fluid Identification in Environmentally Challenged and Laundered Samples

Date Published

May 2019

Publication Type

Research (Applied/Empirical), Report (Study/Research), Report (Grant Sponsored), Program/Project Description

Agencies

NIJ-Sponsored

Production of High- Fidelity Electropherograms Results in Improved and Consistent DNA interpretation Standardizing the forensic validation process

Date Published

November 2017

Publication Type

Research (Applied/Empirical), Report (Study/Research), Report (Grant Sponsored), Program/Project Description

Agencies

NIJ-Sponsored

Sperm Cell Purification From Mock Forensic Swabs Using SOMAmer (TM) Affinity Reagents

Date Published

July 2018

Publication Type

Research (Applied/Empirical), Report (Study/Research), Report (Grant Sponsored), Program/Project Description

Agencies

NIJ-Sponsored

Interpreting Short Tandem Repeat Variations in Humans Using Mutational Constraint

Date Published

2017

Publication Type

Research (Applied/Empirical), Report (Study/Research), Report (Grant Sponsored), Program/Project Description

Agencies

NIJ-Sponsored

Comparative Tolerance of Two Massively Parallel Sequencing Systems to Common PCR Inhibitors

Date Published

2018

Publication Type

Research (Applied/Empirical), Report (Study/Research), Report (Grant Sponsored), Program/Project Description

Agencies

NIJ-Sponsored

Comparative Sensitivity and Inhibitor Tolerance of GlobalFiler PCR Amplification and Investigator 24plex QS Kits for Challenging Samples

Date Published

May 2018

Publication Type

Research (Applied/Empirical), Report (Study/Research), Report (Grant Sponsored), Program/Project Description

Agencies

NIJ-Sponsored

A Large-scale Dataset of Single and Mixed-source Short Tandem Repeat Profiles To Inform Human Identification Strategies: PROVEDIt

Date Published

January 2018

Publication Type

Research (Applied/Empirical), Report (Study/Research), Report (Grant Sponsored), Program/Project Description

Agencies

NIJ-Sponsored

A Broadly Applicable Assay for Rapidly and Accurately Quantifying DNA Surface Coverage on Diverse Particles

Date Published

2017

Agencies

NIJ-Sponsored

Evaluation of Four Commercial Quantitative Real-Time PCR Kits With Inhibited and Degraded Samples

Date Published

2018

Publication Type

Research (Applied/Empirical), Report (Study/Research), Report (Grant Sponsored), Program/Project Evaluation, Program/Project Description

Agencies

NIJ-Sponsored

Optimization of InnoXtract (TM) extraction and purification system for DNA extraction from skeletal samples

Date Published

2023

Publication Type

Research (Applied/Empirical)

Agencies

NIJ-Sponsored

Automation of Sexual Assault DNA Processing Increases Efficiency

Date Published

September 2023

Publication Type

Research (Applied/Empirical)

Agencies

NIJ

Considering DNA damage when interpreting mtDNA heteroplasmy in deep sequencing data

Date Published

2017

Publication Type

Research (Applied/Empirical)

Agencies

NIJ-Sponsored

The Application of Magnetic Bead Hybridization for the Recovery and STR Amplification of Degraded and Inhibited Forensic DNA

Date Published

2011

Publication Type

Research (Applied/Empirical), Report (Study/Research), Report (Grant Sponsored), Program/Project Description

Agencies

NIJ-Sponsored

Target Capture Enrichment of Nuclear SNP Markers for Massively Parallel Sequencing of Degraded and Mixed samples

Date Published

May 2018

Publication Type

Research (Applied/Empirical), Report (Study/Research), Report (Grant Sponsored), Program/Project Description

Agencies

NIJ-Sponsored

Applications of Probe Capture Enrichment Next Generation Sequencing for Whole Mitochondrial Genome and 426 Nuclear SNPs for Forensically Challenging Samples

Date Published

2018

Publication Type

Research (Applied/Empirical), Report (Study/Research), Report (Grant Sponsored), Program/Project Description

Agencies

NIJ-Sponsored

Validation of Illumina’s MiSeq FGx NGS Platform for Transition to Casework

Date Published

September 2017

Agencies

NIJ-Sponsored

When DNA Samples Are Complicated: Calculating Variation in Mixed Samples Interpretation

Date Published

December 12, 2022

NIJ-funded researchers create precision and accuracy statistics to assess variation in the interpretation of complex DNA mixtures.

Massively Parallel Mitogenome Sequencing: Building a Strong Foundation for the Interpretation of MPS MtDNA

DJO-NIJ-22-RO-0005

Open

Funding First Awarded

2021

$624,692

Quantifying the accuracy of low-quality DNA sample analysis from genotyping to genealogical searching and integration as a bioinformatic pipeline

15PNIJ-22-GG-04410-DNAX

Closed

Funding First Awarded

2022

$266,406

High-throughput DNA Sequencing of Environmentally Insulted Latent and Partial Bloody Fingerprints After Visualization with the Nanoscale Columnar-Thin-Film Technique

Date Published

2022

Agencies

NIJ-Sponsored

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