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Working Towards Implementation of Whole Genome Mitochondrial DNA Sequencing into Routine Casework

NCJ Number
Date Published
December 2007
2 pages

The authors describe how their lab is working toward the implementation of whole genome mitochondrial DNA sequencing into routine casework.


Massively parallel sequencing (MPS) technologies offer opportunities to expand forensic mitochondrial DNA (mtDNA) typing capabilities, affording higher resolution, an increase in discrimination power, and potentially enabling mixture interpretation. In addition, improvements to MPS technologies and workflows have made implementation into forensic genetic laboratories increasingly more feasible. Following initial successful studies with the Precision ID mtDNA Whole Genome Panel, the process of internal validation and implementation of whole genome mtDNA sequencing began in the authors Missing Persons and Forensic Casework Units. (publisher abstract modified)

Date Published: December 1, 2007