In response to requests from the forensic community, commercial companies are generating larger, more sensitive, and more discriminating STR multiplexes. These multiplexes are now applied to a wider range of samples including complex multi-person mixtures. In parallel there is an overdue reappraisal of profile interpretation methodology. Aspects of this reappraisal include 1) the need for a quantitative understanding of allele and stutter peak heights and their variability; 2) an interest in reassessing the utility of smaller peaks below the often used analytical threshold; 3) a need to understand not just the occurrence of peak drop-in but also the height distribution of such peaks; and 4) a need to understand the limitations of the multiplex-interpretation strategy pair implemented. (Publisher abstract modified)
Downloads
Similar Publications
- Differential Sampling of Contact Surfaces of Footwear to Separate Fractions of Loosely, Moderately and Tightly Held Particles
- CPU HARDWARE CLASSIFICATION AND PERFORMANCE PREDICTION USING NEURAL NETWORKS AND STATISTICAL LEARNING
- Polymorphic tandem repeats within gene promoters act as modifiers of gene expression and DNA methylation in humans