In response to the September 11, 2001, terrorist attack on the World Trade Center (WTC) in New York City, the New York State Emergency Management Office requested the assistance of the U.S. Department of Justice, National Institute of Justice (NIJ) to provide onsite technology. NIJ’s Office of Science and Technology established a technology support office adjacent to the WTC complex. In addition to the technological assistance provided by NIJ, many valuable recommendations in terms of new technology research and development and in modifying existing technologies were received in the areas of search and rescue assistance, communications and interoperability assistance, excess property and equipment assistance, and investigative and forensic assistance. NIJ’s ability to assist New York City is due in part to its initiation in 1997 through its Office of Science and Technology (OS&T) the Critical Incident Technology Program. The program develops solutions relating to agency coordination, personnel training, and equipment and technology development. The program is a collaborative effort among Federal, State, and local public safety agencies. The report presents a number of new technologies produced through this collaborative effort in the areas of biohazard and chemical defense, communications and interoperability, explosives detection and remediation, security, and weapons detection.