Application of Proteinases for DNA Isolation of Challenged Bone Specimens

The goal of this project is to develop a simple trypsin method for processing challenged bone specimens prior to DNA isolation. Previous results, tested on fresh human bone samples, have suggested that the trypsin method can be potentially useful for forensic DNA analysis. In this research, additional studies will be performed on samples that are more typically encountered in actual forensic cases. If these studies are successful, the method can be used as an alternative cleaning method to procedures such as sanding.

ca/ncf