Description of original award (Fiscal Year 2009, $405,812)
Aptamers are single-stranded nucleic acid molecules with molecular recognition properties comparable to antibodies, although often with even higher specificity. The goal of this project is to develop an assay that uses aptamers to capture and separate spermatozoa found in sexual assault evidence prior to DNA extraction. The assay will allow for the immobilization of spermatozoa on a solid matrix, such as a coated 96-well plate, beads, or other suitable matrices. This sperm-capture assay can be automated for high-throughput processing and could therefore greatly decrease the amount of time required to develop male DNA profiles from sexual assault evidence in a cost effective manner.
- Examining the Black Box: A Formative and Evaluability Assessment of Cross-sectoral Approaches for Intimate Partner and Sexual Violence
- Access to Justice for Adolescents and Young Adults Experiencing Intimate Partner Violence: Effectiveness and Accessibility of Civil Protection Orders
- Preventing the next sext: A behavioral economic approach to understanding nude photo sharing decisions in a high school community