U.S. flag

An official website of the United States government, Department of Justice.

Dot gov

The .gov means it’s official.
Federal government websites always use a .gov or .mil domain. Before sharing sensitive information online, make sure you’re on a .gov or .mil site by inspecting your browser’s address (or “location”) bar.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Development of an Animal Model of Electromuscular Incapacitation Device Induced Malignant Hyperthermia

Award Information

Award #
2007-IJ-CX-K230
Location
Awardee County
Cook
Congressional District
Status
Closed
Funding First Awarded
2007
Total funding (to date)
$676,275

Description of original award (Fiscal Year 2007, $347,625)

The purpose of this project is to develop a standardized animal model of EMI-induced malignant hyperthermia (MHT) by administering drugs known to increase temperature along with EMI stimuli sufficient to precipitate MHT. This project will include analysis of the pathophysiology associated with EMI-induced MHT and an analysis of histopathological changes in tissue damaged by EMI-induced MHT. It will lead to the development of safer, more effective conducted energy devices for law enforcement application.

ca/ncf

The purpose of this project is to develop a standardized animal model of EMI-induced malignant hyperthermia (MHT) by administering drugs known to increase temperature along with EMI stimuli sufficient to precipitate MHT. This project will include analysis of the pathophysiology associated with EMI-induced MHT and an analysis of histopathological changes in tissue damaged by EMI-induced MHT. It will lead to the development of safer, more effective conducted energy devices for law enforcement application.

nca/ncf

Date Created: September 10, 2007