Analysis of Cocaine Analytes in Human Hair: Evaluation of Concentration Ratios in Different Hair Types, Cocaine Sources, Drug User Populations, and Surface-Contaminated Specimens

The objective of this study is to investigate cocaine analyte concentrations in hair to determine if appropriate concentration ratios can be established to distinguish a cocaine user from a non-user. The project will evaluate metabolite-to-parent drug concentration ratios in human hair to include variables such as hair type (e.g., color, texture), cocaine source (e.g., pharmaceutical, "street" drug), and specimen type (e.g., drug user in street environment, drug user in controlled research environment, internal drug fortification, and surface-contaminated). ca/ncf