Gene Polymorphism and Human Pigmentation

This is supplement #1 to award 2002-IJ-CX-K010. The first phase of this project included a comprehensive population study to identify and characterize polymorphisms that can predict hair, skin, and eye pigmentation in normal individuals. Statistical tests to determine the robustness of the models have been successful. Supplemental studies will include a blind study of 250 individuals (to further test the models), development of a multiplexed PCR analytical method (to be performed in collaboration with NIST), evaluation of the assay on simulated biological evidence, and performance of SWGDAM developmental validation studies. nca/ncf