Toxicology

The NIJ Forensic Science Research and Development Symposium is an open meeting where attendees can learn about NIJ-funded research across a variety of forensic science areas. 

In this specialized workshop intended for forensic science service providers (FSSPs), we explore the increasing adoption of Time-of-Flight and Quadrupole Time-of-Flight Mass Spectrometry (TOF/QTOF-MS) technologies within forensic laboratories. The session provides an in-depth examination of various critical stages, encompassing planning, validation methodologies, analytical techniques, data review processes, and report generation. Subject matter experts disseminate knowledge and share first-hand experiences related to the utilization of TOF/QTOF-MS technology.

In this specialized workshop intended for forensic science service providers (FSSPs), we explore the increasing adoption of Time-of-Flight and Quadrupole Time-of-Flight Mass Spectrometry (TOF/QTOF-MS) technologies within forensic laboratories. The session provides an in-depth examination of various critical stages, encompassing planning, validation methodologies, analytical techniques, data review processes, and report generation. Subject matter experts disseminate knowledge and share first-hand experiences related to the utilization of TOF/QTOF-MS technology.

This session provides an overview of the fundamental principles of statistics as encountered and applied in forensic toxicology. Various elements of statistics are often utilized or relied upon by scientists to describe produced results and to demonstrate if forensic instruments or processes are “working” or “in-control”. Here we establish the basic terminology for the principles of statistical analysis. Participants will begin to be better equipped to interpret and analyze forensic toxicology data accurately and effectively. 

In this fireside chat, session six of the the Foundational Statistics for Forensic Toxicology series, panelists include practitioners and experts in forensic toxicology, and subject matter experts for the application of statistics in forensic toxicology. Join us in a dynamic and engaging session to explore common frustrations and challenges experienced in the laboratory, providing participants with valuable insights and practical solutions.

Session five of the Foundational Statistics for Forensic Toxicology series will incorporate concepts from earlier sessions and focus on the practical application of control data in estimating Measurement Uncertainty (MU). Rather than a discussion about how to calculate the MU, this session provides practical examples to demonstrate the key elements of the statistical process. Participants will learn how to incorporate control data into MU estimation by leveraging statistical techniques aimed at quantifying the uncertainty associated with measurement processes.

This second session in the  Foundational Statistics for Forensic Toxicology series explores various distributions commonly encountered in forensic toxicology (normal, rectangular, etc.). Participants will learn about the characteristics of these distributions and how they manifest in toxicological data. Also, this session covers statistical measures that can describe and compare distributions, including variance, standard deviation, and relative standard deviation.

This third session of the Foundational Statistics for Forensic Toxicology series explores hypothesis testing, a fundamental concept in statistical analysis, and its applications in forensic toxicology. Participants will gain an understanding of the different types of statistical tests, their respective applications, and how they can be utilized to uncover meaningful insights from toxicological data. 

In this fourth session of the Foundational Statistics for Forensic Toxicology series, we address common challenges, misconceptions, and questions encountered in day-to-day forensic toxicology laboratory settings related to statistics. Participants will gain insights into the practical application of statistical concepts and terminology in quality control and control charting, including trends and outliers. Furthermore, participants will learn about data interpretation, distinguishing between results that occur due to statistical significance and those the occur due to random variation.

With the rise of illicit fentanyl, fentanyl analogues, synthetic cathinones, xylazine, and other substances adulterating many traditional street drugs, users often have no idea what they are consuming, leading to overdose and death.  This further complicates toxicology testing and death determination.  This presentation will cover interesting postmortem case studies from Ohio, Denver, and Miami from the scene perspective through autopsy and toxicology testing.