Description of original award (Fiscal Year 2010, $499,198)
The goal of this work is to assemble and test a four-site (i.e., four sample cartridges operating in parallel) integrated microfluidic controlled microarray system for SNP-based typing of phenotypic markers. In the previously completed Phase I, researchers demonstrated feasibility of the methods and developed components of the system. Phase II which is nearing completion, will result in optimized protocols and assay chemistries for phenotype determination, and a prototype of the integrated system. Phase III will upgrade the current Phase II breadboard prototype from accepting a single cartridge to processing four cartridges in parallel.
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