Development of a SNP Assay Panel for Ancestral Origin Inference and Individuals Somatic Traits

The goal of this work is to develop a sensitive and robust Single Base Primer Extension (SBE) assay for combined ancestry and phenotype inference using Single Nucleotide Polymorphisms (SNPs). The assay, which can be performed on equipment commonly found in operational crime laboratories, would be of value when a DNA profile obtained from crime scene evidence does not match identified suspects or profiles from available databases. Having phenotype or ancestry information in these cases would increase the ability to identify individuals related to a crime scene.

ca/ncf