Identification and Separation of Same Gender Mixtures of Various Cell Types Using Interphase FISH Techniques and Laser Microdissection

The goal of this project is to develop improved methods for separation of the components of same gender mixtures (for example, epithelial cells from more than one male) encountered in biological evidence. The research will focus on using fluorescent probes based upon genetic polymorphisms capable of distinguishing same gender individuals, in combination with laser microdissection, which is used to separate and remove the cells for subsequent DNA analysis. ca/ncf