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This webinar seeks to describe how preemptive synthesis and characterization of potent psychoactive substances from the literature can aid forensic scientists in the identification of unknowns appearing in samples emerging from illicit markets. Additionally, the presenter seeks to provide understanding of how gaps in pharmacological knowledge of old drugs can be exploited to find new emerging synthetic drugs. This webinar will cover the following topics in detail:
- Combinatorial approaches with commercially available starting materials to create both reported and novel analogs within each of the series.
- Activity and potency of emerging opioid analogs at cloned and expressed hMOR.