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Categorical Methods for the Interpretation of RNA Profiles as Cell Type Evidence and Their Limitations

NCJ Number
255155
Date Published
December 2015
Length
3 pages
Author(s)
Jacob de Zoete; James Curran; Marjan Sjerps
Agencies
NIJ-Sponsored
Publication Type
Research (Applied/Empirical), Report (Study/Research), Report (Grant Sponsored), Instructional Material
Grant Number(s)
2014-DN-BX-K028
Annotation
This article discusses four popular methods for the interpretation of RNA evidence.
Abstract
Existing methods for the interpretation of RNA profiles as evidence for the presence of certain cell types aim for making categorical statements. Such statements limit the possibility to report the associated uncertainty. From a statistical point of view, a probabilistic approach is a preferable choice. (publisher abstract modified)
Date Created: July 20, 2021