Development and Production of Reference Materials for Control and Calibration of Hair Drug Testing

The primary purpose of this project is to develop and produce a reference material of hair fortified with controlled substances for use by forensic laboratories as controls and/or calibrators to identify and measure drugs of abuse in hair. Drug analytes will be extracted from the hair matrix by either gas chromatography/mass spectrometry and/or liquid chromatography/tandem mass spectrometry analyses. All samples and data will be processed using procedures routinely used in hair-testing laboratories and accepted by the scientific community (e.g., ion ratios, quality control samples, internal standards). ca/ncf